SINDROME ANTIFOSFOLIPIDO PDF

Eine serodiagnostiche Reaktion bei Syphilis. Deutsche Med Wochenschr ; Pangborn MC. A new serologically active phospholipid from beefbei Syphilis. Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus. Lancet ;2:

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El territorio cerebral afectado mas frecuentemente es el de la arteria cerebral media. Se presenta por lo general en la cara anterior de piernas y brazos. Figura 1. Digestivas Las manifestaciones digestivas del SAF son infrecuentes.

No se utiliza en la actualidad por su escasa sensibilidad. Tabla 2. Debe descartarse la presencia de vasculitis 2. Por lo tanto, se debe individualizar el tratamiento en conjunto con la paciente. Las evidencias disponible para recomendar en pacientes diagnosticados de un SAF el empleo de nuevos anticoagulantes orales dabigatran, apixaban o rivaroxaban son insuficientes.

Prophylaxis of the antiphospholipid syndrome: a consensus report. Lupus ; Chest ; S. Catastrophic antiphospholipid syndrome. Clinical and laboratory features of 50 patients. Medicine Baltimore ; Antiphospholipid antibody associated thrombocytopenia and the paradoxical risk of thrombosis. Barbhaiya M, Erkan D. Primary thrombosis prophylaxis in antiphospholipid antibody-positive patients: where do we stand?

Curr Rheumatol Rep ; Rituximab use in the catastrophic antiphospholipid syndrome: descriptive analysis of the CAPS registry patients receiving rituximab. Autoimmun Rev ; Antiphospholipid antibody tests: spreading the net. Ann Rheum Dis ; A review of the sapporo and revised Sapporo criteria for the classification of antiphospholipid syndrome. Where do the revised sapporo criteria add value? J Rheumatol ; Laboratory identification of lupus anticoagulants: results of the Second International Workshop for Identification of Lupus Anticoagulants.

Thromb Haemost ; Catastrophic antiphospholipid syndrome: task force report summary. New oral anticoagulants in thrombotic antiphospholipid syndrome. A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome.

N Engl J Med ; Low-dose aspirin vs low-dose aspirin plus low-intensity warfarin in thromboprophylaxis: a prospective, multicentre, randomized, open, controlled trial in patients positive for antiphospholipid antibodies ALIWAPAS.

Rheumatology Oxford ; Can neurologic manifestations of Hughes antiphospholipid syndrome be distinguished from multiple sclerosis? Analysis of 27 patients and review of the literature. Devreese K, Hoylaerts MF. Challenges in the diagnosis of the antiphospholipid syndrome. Clin Chem ; Correction of thrombocytopenia with dapsone in the primary antiphospholipid syndrome. Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice. Circulation ; Aspirin for primary thrombosis prevention in the antiphospholipid syndrome: a randomized, double-blind, placebo-controlled trial in asymptomatic antiphospholipid antibody-positive individuals.

Arthritis Rheum ; Perioperative medical management of antiphospholipid syndrome: hospital for special surgery experience, review of literature, and recommendations. High thrombosis rate after fetal loss in antiphospholipid syndrome: effective prophylaxis with aspirin. A pilot open-label phase II trial of rituximab for non-criteria manifestations of antiphospholipid syndrome. A cross-sectional study of clinical thrombotic risk factors and preventive treatments in antiphospholipid syndrome.

How we diagnose the antiphospholipid syndrome. Blood ; Antiphospholipid antibodies and venous thromboembolism. Home treatment of deep venous thrombosis with low molecular weight heparin: Long-term incidence of recurrent venous thromboembolism. Am J Hematol ; Influence of aspirin on the clinical outcomes of anti-phospholipid antibodies-positive patients. Chest ; eS.

The protective effect of antimalarial drugs on thrombovascular events in systemic lupus erythematosus. Warfarin and the antiphospholipid syndrome: does one size fit all?

Assessment of the revised antiphospholipid syndrome classification criteria. Kavanaugh A. Danazol therapy in thrombocytopenia associated with the antiphospholipid antibody syndrome. Ann Intern Med ; Efficacy of eculizumab in a patient with immunoadsorption-dependent catastrophic antiphospholipid syndrome: a case report.

Medicine Baltimore ; e Kumar D, Roubey RA. Use of rituximab in the antiphospholipid syndrome. Management of immune thrombocytopenic purpura associated with the antiphospholipid antibody syndrome. Clin Exp Rheumatol ; The antiphospholipid syndrome. A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein thrombosis.

Lockshin MD, Erkan D. Treatment of the antiphospholipid syndrome. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome APS. J Thromb Haemost ; Muscal E, Brey RL.

Neurologic manifestations of the antiphospholipid syndrome: integrating molecular and clinical lessons. Update of the guidelines for lupus anticoagulant detection. Proposals for the measurement of anti-beta2-glycoprotein I antibodies. Standardization group of the European Forum on Antiphospholipid Antibodies. Antiphospholipid thrombosis: clinical course after the first thrombotic event in 70 patients. Prevalence and clinical significance of anti-phospholipid antibodies in multiple sclerosis: a study of 89 patients.

J Autoimmun ; Rituximab treatment for resistant antiphospholipid syndrome. Risk factors for a first thrombotic event in antiphospholipid antibody carriers. A multicentre, retrospective follow-up study. Antiphospholipid syndrome. Lancet ; Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at the 13th International Congress on antiphospholipid antibodies.

A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies. The treatment of antiphospholipid syndrome: a harmonic contrast. Best Pract Res Clin Rheumatol ; Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review. Anticardiolipin antibodies predict early recurrence of thromboembolism and death among patients with venous thromboembolism following anticoagulant therapy.

Duration of Anticoagulation Study Group. Am J Med ; Management of venous thromboembolism: a systematic review for a practice guideline.

Prophylactic antithrombotic therapy for patients with systemic lupus erythematosus with or without antiphospholipid antibodies: do the benefits outweigh the risks? A decision analysis. Arch Intern Med ; Win K, Rodgers GM.

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