Sagrel Close-up of the leaves Photograph by: Is it possible to have leaves shipped to the United States xuratella bulk or would they have to be in a vacuum sealed format? Gives lots of plant uses as well as information on plant habit and habitat. Young growth Photograph by: Now containing plants. Ang Wikimedia Commons may mga payl nga may kalabotan sa: Curatella americana Siyentipiko nga klasipikasyon Ginharian: Paghimo ni bot Lsjbot.
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This article has been cited by other articles in PMC. Abstract High levels of reactive oxygen species in the body and hyperlipidemia are key factors for the development of cardiovascular diseases such as atherosclerosis.
The present study investigated the antioxidant and hypolipidemic activity of hydroethanolic extract of Curatella americana L. ExC revealed IC50 of 6. Together, the results showed the antioxidant activity of ExC and its ability to improve the serum lipid profile in hyperlipidemic rats. Introduction Hyperlipidemia causes about 17 million deaths worldwide each year [ 1 ]; in addition, it is also a key factor for the development of heart and coronary diseases and atherosclerosis.
Atherosclerosis is a chronic inflammatory disease triggered by multiple factors, with strong contribution of endothelial damage related to lipid peroxidation. This endothelial dysfunction increases the permeation of low-density lipoproteins LDL through the intima layer, resulting in oxidation and formation of atherosclerotic damage [ 2 , 3 ].
In order to control this imbalance, the body has enzymatic and nonenzymatic antioxidant defense mechanisms [ 4 ] capable of preventing the deleterious effects of oxidation, inhibiting lipid peroxidation, free radicals scavenging, and maintaining redox balance in cells. In addition to endogenous antioxidants, there are antioxidants from exogenous sources.
The beneficial effects of foods have been linked to the presence of bioactive compounds and other nutrients. Examples of biomolecules that have antioxidant potential are phenolic compounds such as isoflavones, phenolic acids, catechins, chlorogenic acids, anthocyanins, and terpenes [ 5 ].
Thus, plants have been described as an alternative to the development of new drugs [ 6 ] applied to treatment of many diseases such as hypercholesterolemia, ulcers, depurative blood, and cancer [ 7 — 9 ]. Curatella americana L. The beneficial effects of C. The anti-inflammatory, analgesic, antihypertensive, and vasodilator effects of the hydroethanolic extract of Curatella americana L.
In folk medicine, leaf decoction is used as an antiseptic and astringent; bark infusion is used for the treatment of cold and healing wounds, ulcers, diabetes, and hypertension [ 14 ]. In this context, the aim of this study was to evaluate the antioxidant and hypolipidemic activity of the hydroethanolic extract of Curatella americana L. Material and Methods 2. Plant Material and Extract Preparation C. Dosage of Phenolic Compounds, Total Flavonoids, and Saponins The concentration of phenolic compounds in samples was determined by the spectrophotometric method described by [ 15 ] using the Folin-Ciocalteu method.
Three ExC measurements were performed, the average being presented in mg of gallic acid equivalents GAE per g of sample. About 0. After 30 min at rest, the absorbance of solutions was read at nm. The presence of saponins was evaluated by preparing 10 mg of ExC dissolved in 2 mL of ethanol.
Then, 5 mL of boiling water was added; the sample was vigorously shaken and allowed to stand for 20 min. According to [ 17 ], foaming indicates the presence of saponins. DPPH solutions were prepared 0. Serial dilutions were prepared based on these solutions in the concentrations investigated. To establish the half-maximal inhibitory concentration IC50 of DPPH free radical scavenging, the samples were tested in serial dilutions 0.
Samples were assessed by spectrophotometer at nm. The absorbance of each sample was divided by the absorbance of DPPH and multiplied by one hundred to represent the antioxidant activity in percentage. All independent experiments were performed in triplicate. The buffy coat was removed from plasma. The remaining erythrocytes underwent three washes with saline 0. Aliquots were taken every 60 min after the start of incubation for min, which were read in spectrophotometer at nm.
Three independent experiments were performed in duplicate. For this, after the incubation period, an aliquot of 0. An aliquot of 0.
After this period, samples were kept at room temperature for 15 min, followed by addition of 3 mL of butanol with subsequent agitation and centrifugation as described by [ 20 ]. Reading of the supernatant absorbance was carried out in spectrophotometer at nm. Concomitantly, normoglycemic rats were kept in commercial rodent chow Labina during all experimental period constituting the control group control diet group, CD.
All rats were kept in controlled light cycle and temperature with feed and water being offered ad libitum. At the end of treatment and after euthanasia, organs, tissue, and blood were collected for analysis. Results 3.
Antioxidant Activity Considering the presence of potentially antioxidant substances in ExC, an in vitro evaluation of DPPH free radical scavenging at different concentrations was performed.
Curatella americana L.
General Description. Chaparro in English is known as the rough-leaf tree and it is also known as careicillo, peralejo macho, vacabuey, aperalejo, curatela, peralejo, peralejo de sabana, pomme torche, raspa viejo, tlachicn, hoja man, yaha, lengua de vaca, malcajaco, hoja chige, raspa, raspa guacal, chumico de palo, hoja chige, yahal, saha, chumico, azufre, curata, paric, chaparro de sabana, chaparro sabanero, chaparro colorado, parica, feuille rude, curatahie, carne de fiambre, caimbe, cajueiro bravo, sambaiba, caimbahiba, cambaiba, sobro, sabaibinha, and chaco Liogier , , Standley and Record , Salas Estrada , Siegel and Paguaga , Vargas Ulate , Standley , , Prez Arbelaez , Record and Mell , Bastos , Kileen and others Curatlla means plants being used or worked, for example, for polishing weapons and metal Bailey It is an evergreen woody shrub less than 50 cm tall to a tree 6 to 10 m in height Lundell , Liogier , Killeen and others Its most frequent habit is that of a gnarled shrub or small tree Sarmiento and Monasterio Leaves are simple, alternate, oval to elliptic oval, 5 to 12 cm wide and 10 to 15 cm long, rounded to emarginated, pinnately veined, hard, pubescent when young , and with very scabrous surfaces and sinuous margins Pittier , Gentry , Killeen and others
Samujinn Oxidative Medicine and Cellular Longevity Solitary tree in an arid landscape Photograph by: Kining maong panid kataposang giusab niadtong 13 Enero sa It can be downloaded from the Internet. Comments have to be approved before they are shown here. Curatella glabra Spruce ex Benth. Curatella americana Stunning photographs of each species, brief details on the plant, its uses and how to cyratella it from seed.